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Zuo,G.;Kang,S.-g.;Xiu,P.;Zhao,Y.;Zhou,R. Interactions Between Proteins and Carbon-Based Nanoparticles: Exploring the Origin of Nanotoxicity at the Molecular Level. Small 2013,9 (9-10),1546-1556,Review. DOI: 10.1002/smll.201201381.
Zhang,X.;He,X.;Li,Y.;Zhang,Z.;Ma,Y.;Li,F.;Liu,J. A Cytotoxicity Study of Fluorescent Carbon Nanodots Using Human Bronchial Epithelial Cells. Journal of Nanoscience and Nanotechnology 2013,13 (8),5254-5259. DOI: 10.1166/jnn.2013.7528.
Yan,L.;Gu,Z.;Zhao,Y. Chemical Mechanisms of the Toxicological Properties of Nanomaterials: Generation of Intracellular Reactive Oxygen Species. Chemistry-an Asian Journal 2013,8 (10),2342-2353,Review. DOI: 10.1002/asia.201300542.
Xue,L.;He,X.;Li,Y.;Qu,M.;Zhang,Z. Pulmonary Toxicity of Ceria Nanoparticles in Mice After Intratracheal Instillation. Journal of Nanoscience and Nanotechnology 2013,13 (10),6575-6580. DOI: 10.1166/jnn.2013.7216.
Xu,Y.;Lin,X.;Chen,C. Key factors influencing the toxicity of nanomaterials. Chinese Science Bulletin 2013,58 (24),2466-2478.
Wang,Y.;Wang,P.;Chen,C.;Zhao,Y. Cellular and molecular mechanisms of pulmonary toxicity caused by carbon nanotubes with various physiochemical properties. Chinese Science Bulletin 2013,58 (21),2007-2020,Review.
Meng,J.;Xing,J.;Ma,X.;Cao,W.;Lu,J.;Wang,Y.;Gao,X.;Sun,B.;Liang,X.;Zhao,Y.RETRACTED: Metallofullerol nanoparticles with low toxicity inhibit tumor growth by induction of G0/G1 arrest (Retracted article. See vol. 8,pg. 1356,2013). Nanomedicine 2013,8 (2),203-213,;Retracted Publication. DOI: 10.2217/nnm.12.95.
Lu,X.;Liu,Y.;Kong,X.;Lobie,P. E.;Chen,C.;Zhu,T. Nanotoxicity: A Growing Need for Study in the Endocrine System. Small 2013,9 (9-10),1654-1671,Review. DOI: 10.1002/smll.201201517.
Liu,Y.;Zhao,Y.;Sun,B.;Chen,C. Understanding the Toxicity of Carbon Nanotubes. Accounts of Chemical Research 2013,46 (3),702-713,Review. DOI: 10.1021/ar300028m.
Chen,X.-X.;Cheng,B.;Yang,Y.-X.;Cao,A.;Liu,J.-H.;Du,L.-J.;Liu,Y.;Zhao,Y.;Wang,H. Characterization and Preliminary Toxicity Assay of Nano-Titanium Dioxide Additive in Sugar-Coated Chewing Gum. Small 2013,9 (9-10),1765-1774. DOI: 10.1002/smll.201201506.
Chen,C.;Li,Y.-F.;Qu,Y.;Chai,Z.;Zhao,Y. Advanced nuclear analytical and related techniques for the growing challenges in nanotoxicology. Chemical Society Reviews 2013,42 (21),8266-8303,Review. DOI: 10.1039/c3cs60111k.
Zhang,P.;Ma,Y.;Zhang,Z.;He,X.;Guo,Z.;Tai,R.;Ding,Y.;Zhao,Y.;Chai,Z. Comparative toxicity of nanoparticulate/bulk Yb2O3 and YbCl3 to cucumber (Cucumis sativus). Environmental Science & Technology 2012,46 (3),1834-1841. DOI: 10.1021/es2027295.
Zhang,L.;Bai,R.;Liu,Y.;Meng,L.;Li,B.;Wang,L.;Xu,L.;Le Guyader,L.;Chen,C. The dose-dependent toxicological effects and potential perturbation on the neurotransmitter secretion in brain following intranasal instillation of copper nanoparticles. Nanotoxicology 2012,6 (5),562-575. DOI: 10.3109/17435390.2011.590906.
Yin,J.-J.;Liu,J.;Ehrenshaft,M.;Roberts,J. E.;Fu,P. P.;Mason,R. P.;Zhao,B. Phototoxicity of nano titanium dioxides in HaCaT keratinocytes-Generation of reactive oxygen species and cell damage. Toxicology and Applied Pharmacology 2012,263 (1),81-88. DOI: 10.1016/j.taap.2012.06.001.
Xue,Y.;Zhang,S.;Huang,Y.;Zhang,T.;Liu,X.;Hu,Y.;Zhang,Z.;Tang,M. Acute toxic effects and gender-related biokinetics of silver nanoparticles following an intravenous injection in mice. Journal of Applied Toxicology 2012,32 (11),890-899. DOI: 10.1002/jat.2742.
He,X.;Kuang,Y.;Li,Y.;Zhang,H.;Ma,Y.;Bai,W.;Zhang,Z.;Wu,Z.;Zhao,Y.;Chai,Z. Changing exposure media can reverse the cytotoxicity of ceria nanoparticles for <i>Escherichia coli</i>. Nanotoxicology 2012,6 (3),233-240. DOI: 10.3109/17435390.2011.569097.
Ge,C.;Li,Y.;Yin,J.-J.;Liu,Y.;Wang,L.;Zhao,Y.;Chen,C. The contributions of metal impurities and tube structure to the toxicity of carbon nanotube materials. Npg Asia Materials 2012,4. DOI: 10.1038/am.2012.60.
Chen,C. Hot Topic: Pharmaceutical Kinetics and Toxicological Effects of Nanosystems and Nanomaterials for Biomedical Applications. Current Drug Metabolism 2012,13 (8),1033-1034,Editorial Material. DOI: 10.2174/138920012802850065.
Chang,Y.-N.;Zhang,M.;Xia,L.;Zhang,J.;Xing,G. The Toxic Effects and Mechanisms of CuO and ZnO Nanoparticles. Materials 2012,5 (12),2850-2871,Review. DOI: 10.3390/ma5122850.
(2011年以前)该研究方向的主要发表论文如下:
Ge,C. C.;Du,J. F.;Zhao,L. N.;Wang,L. M.;Liu,Y.;Li,D. H.;Yang,Y. L.;Zhou,R. H.;Zhao,Y. L.;Chai,Z. F.;Chen,C. Y.,Binding of blood proteins to carbon nanotubes reduces cytotoxicity. PNAS 2011, 108(41 ),16968-16973.
Li,Y. Y.;Zhou,Y. L.;Wang,H. Y.;Perrett,S.;Zhao,Y. L.;Tang,Z. Y.;Nie,G. J.,Chirality of Glutathione Surface Coating Affects the Cytotoxicity of Quantum Dots. Angewandte Chemie International Edition 2011, 50 (26),5860-5864.
Zhu,M. T.;Wang,B.;Wang,Y.;Yuan,L.;Wang,H. J.;Wang,M.;Ouyang,H.;Chai,Z. F.;Feng,W. Y.;Zhao,Y. L.,Endothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: Risk factors for early atherosclerosis. Toxicology Letters 2011 203 (2),162-171.
Zhang,L.;Bai,R.;Li,B.;Ge,C.;Du,J.;Liu,Y.;Le Guyader,L.;Zhao,Y.;Wu,Y.;He,S.;Ma,Y.;Chen,C.,Rutile TiO(2) particles exert size and surface coating dependent retention and lesions on the murine brain. Toxicology Letters 2011, 207 (1),73-81.
Wang,Y.;Wang,B.;Zhu,M. T.;Li,M.;Wang,H. J.;Wang,M.;Ouyang,H.;Chai,Z. F.;Feng,W. Y.;Zhao,Y. L.,Microglial activation,recruitment and phagocytosis as linked phenomena in ferric oxide nanoparticle exposure. Toxicology Letters 2011, 205,26-37.
He,X.;Kuang,Y. S.;Li,Y. Y.;Zhang,H. F.;Ma,Y. H.;Bai,W.;Zhang,Z. Y.;Wu,Z. Q.;Zhao,Y. L.;Chai,Z. F.,Changing exposure media can reverse the cytotoxicity of ceria nanoparticles for Escherichia coli. Nanotoxicology 2011 DOI:10.3109/17435390.2011.569097.
Zhao,F.;Zhao,Y.;Liu,Y.;Chang,X. L.;Chen,C. Y.;Zhao,Y. L.,Cellular Uptake,Intracellular Trafficking and Cytotoxicity of Nanomaterials. Small 2011, 7 (10),1322-1337
Zhang,Z. Y.;Zhao,Y. L.;Chai,Z. F.,Nuclear analytical techniques for nanotoxicology studies. Proc. Radiochim. Acta 2011, 1,345-348.
Yan,L.;Zhao,F.;Li,S. F.;Hu,Z. B.;Zhao,Y. L.,Low-toxic and safe nanomaterials by surface-chemical design,carbon nanotubes,fullerenes,metallofullerenes,and graphenes. Nanoscale 2011, 3 (2),362-382.
Ma,Y. H.;He,X.;Zhang,P.;Zhang,Z. Y.;Guo,Z.;Tai,R. Z.;Xu,Z. J.;Zhang,L. J.;Ding,Y. Y.;Zhao,Y. L.;Chai,Z. F.,Phytotoxicity and biotransformation of La2O3 nanoparticles in a terrestrial plant cucumber (Cucumis sativus). Nanotoxicology 2011,5 (4),743-753.
Ge,C. C.;Meng,L.;Xu,L. G.;Bai,R.;Du,J. F.;Zhang,L.;Li,Y.;Chang,Y. Z.;Zhao,Y. L.;Chen,C. Y.,Acute pulmonary and moderate cardiovascular responses of spontaneously hypertensive rats after exposure to single-wall carbon nanotubes. Nanotoxicology 2011, doi:10.3109/17435390.2011.587905.
Feng,W. Y.;Wang,M.;Guan,M.;Hui,Y.;Shi,J. W.;Wang,B.;Zhu,M. T.;Ouyang,H.;Zhao,Y. L.;Chai,Z. F.,Mercury speciation and mercury-binding protein study by HPLC-ICP-MS on the estimation of mercury toxicity between maternal and infant rats. J. Anal. At. Spectrom. 2011, 26 (1),156-164.
Zhao,Y. L.,Crossroads of nanosafety and their biological effects. Toxicology Letters 2010, 196 S4-S5.
Zhang,H. F.;He,X.;Bai,W.;Guo,X. M.;Zhang,Z. Y.;Chai,Z. F.;Zhao,Y. L.,Ecotoxicological assessment of lanthanum with Caenorhabditis elegans in liquid medium. Metallomics 2010, 2 (12),806 - 810.
Yang,S. T.;Liu,J. H.;Wang,J.;Yuan,Y.;Cao,A. N.;Wang,H. F.;Liu,Y. F.;Zhao,Y. L.,Cytotoxicity of Zinc Oxide Nanoparticles: Importance of Microenvironment. Journal of Nanoscience and Nanotechnology 2010, 10 (12),8638-8645.
Wang,B.;Wang,Z.;Feng,W. Y.;Wang,M.;Hu,Z. B.;Chai,Z. F.;Zhao,Y. L.,New methods for nanotoxicology: synchrotron radiation-based techniques. Analytical and Bioanalytical Chemistry 2010, 398,667-676.
Ma,Y. H.;Kuang,L. L.;He,X.;Bai,W.;Ding,Y. Y.;Zhang,Z. Y.;Zhao,Y. L.;Chai,Z. F.,Effects of rare earth oxide nanoparticles on root elongation of plants. Chemosphere 2010, 78 (3),273-279.
He,X.;Zhang,H. F.;Ma,Y. H.;Bai,W.;Zhang,Z. Y.;Lu,K.;Ding,Y. Y.;Zhao,Y. L.;Chai,Z. F.,Lung deposition and extrapulmonary translocation of nano-ceria after intratracheal instillation. Nanotechnology 2010, 21 (28),285103 (8pp).
Bai,W.;Zhang,Z. Y.;Tian,W. J.;He,X.;Ma,Y. H.;Zhao,Y. L.;Chai,Z. F.,Toxicity of zinc oxide nanoparticles to zebrafish embryo: a physicochemical study of toxicity mechanism. Journal of Nanoparticle Research 2010, 12 (5),1645-1654.
Zhu,M. T.;Feng,W. Y.;Wang,Y.;Wang,B.;Wang,M.;Ouyang,H.;Zhao,Y. L.;Chai,Z. F.,Particokinetics and extrapulmonary translocation of intratracheally instilled ferric oxide nanoparticles in rats and the potential health risk assessment. Toxicological Sciences 2009, 107 (2),342-351.
Zhang,Z. Y.;Zhao,Y. L.;Chai,Z. F.,Applications of radiotracer techniques for the pharmacology and toxicology studies of nanomaterials. Chinese Science Bulletin 2009, 54 (2),173-182.
Wang,B.;Feng,W. Y.;Zhu,M. T.;Wang,Y.;Wang,M.;Gu,Y. Q.;Ouyang,H.;Wang,H. J.;Li,M.;Zhao,Y. L.;Chai,Z. F.;Wang,H. F.,Neurotoxicity of low-dose repeatedly intranasal instillation of nano- and submicron-sized ferric oxide particles in mice. Journal of Nanoparticle Research 2009, 11 (1),41-53.
Lao,F.;Li,W.;Han,D.;Qu,Y.;Liu,Y.;Zhao,Y. L.;Chen,C. Y.,Fullerene derivatives protect endothelial cells against NO-induced damage. Nanotechnology 2009, 20 (22),225103(9pp).
Zhu,M. T.;Feng,W. Y.;Wang,B.;Wang,T. C.;Gu,Y. Q.;Wang,M.;Wang,Y.;Ouyang,H.;Zhao,Y. L.;Chai,Z. F.,Comparative study of pulmonary responses to nano- and submicron-sized ferric oxide in rats. Toxicology 2008, 247 (2-3),102-111.
Zhao,Y. L.;Xing,G. M.;Chai,Z. F.,Nanotoxicology: Are Carbon Nanotubes Safe?Nature Nanotechnology 2008, 3 (4),191-192.
Wang,J. X.;Liu,Y.;Jiao,F.;Lao,F.;Li,W.;Gu,Y. Q.;Li,Y. F.;Ge,C. C.;Zhou,G. Q.;Li,B.;Zhao,Y. L.;Chai,Z. F.;Chen,C. Y.,Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO2 nanoparticles. Toxicology 2008, 254 (1-2),82-90.
Wang,J. X.;Chen,C. Y.;Liu,Y.;Jiao,F.;Li,W.;Lao,F.;Li,Y. F.;Li,B.;Ge,C. C.;Zhou,G. Q.;Gao,Y.;Zhao,Y. L.;Chai,Z. F.,Potential neurological lesion after nasal instillation of TiO2 nanoparticles in the anatase and rutile crystal phases. Toxicology Letters 2008, 183 (1-3),72-80.
Wang,J.;Deng,X. Y.;Yang,S. T.;Wang,H. F.;Zhao,Y. L.;Liu,Y. F.,Rapid translocation and pharmacokinetics of hydroxylated single-walled carbon nanotubes in mice. Nanotoxicology 2008, 2 (1),28-32.
Wang,B.;Feng,W. Y.;Wang,M.;Wang,T. C.;Gu,Y. Q.;Zhu,M. T.;Ouyang,H.;Shi,J. W.;Zhang,F.;Zhao,Y. L.;Chai,Z. F.;Wang,H. F.;Wang,J.,Acute toxicological impact of nano- and submicro-scaled zinc oxide powder on healthy adult mice. Journal of Nanoparticle Research 2008, 10 (2),263-276.
He,X.;Zhang,Z. Y.;Zhang,H. F.;Zhao,Y. L.;Chai,Z. F.,Neurotoxicological evaluation of long-term lanthanum chloride exposure in rats. Toxicological Sciences 2008, 103 (2),354-361.
Chen,Z.;Meng,H.;Xing,G. M.;Yuan,H.;Zhao,F.;Liu,R.;Chang,X. L.;Gao,X. Y.;Wang,T. C.;Jia,G.;Ye,C.;Chai,Z. F.;Zhao,Y. L.,Age-related differences in pulmonary and cardiovascular responses to SiO2 nanoparticle inhalation: Nanotoxicity shows susceptible population. Environmental Science & Technology 2008, 42 (23),8985-8992.
Chen,Z.;Chen,H.;Meng,H.;Xing,G. M.;Gao,X. Y.;Sun,B. Y.;Shi,X. L.;Yuan,H.;Zhang,C. C.;Liu,R.;Zhao,F.;Zhao,Y. L.;Fang,X. H.,Bio-distribution and metabolic paths of silica coated CdSeS quantum dots. Toxicology and Applied Pharmacology 2008, 230 (3),364-371.
Wang,J. X.;Zhou,G. Q.;Chen,C. Y.;Yu,H. W.;Wang,T. C.;Ma,Y. M.;Jia,G.;Gao,Y. X.;Li,B.;Sun,J.;Li,Y. F.;Jiao,F.;Zhao,Y. L.;Chai,Z. F.,Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration. Toxicology Letters 2007, 168 (2),176-185.
Meng,H.;Chen,Z.;Xing,G. M.;Yuan,H.;Chen,C. Y.;Zhao,F.;Zhang,C. C.;Zhao,Y. L.,Ultrahigh reactivity provokes nanotoxicity: Explanation of oral toxicity of nano-copper particles. Toxicology Letters 2007, 175 (1-3),102-110.
Meng,H.;Chen,Z.;Xing,G. M.;Yuan,H.;Chen,C. Y.;Zhao,F.;Zhang,C. C.;Wang,Y.;Zhao,Y. L.,Ultrahigh Reactivity and Grave Nanotoxicity of Copper Nanoparticles. Journal of Radioanalytical and Nuclear Chemistry 2007, 272 (3),595-598.
He,X.;Feng,L. X.;Xiao,H. Q.;Li,Z.;Liu,N. Q.;Zhao,Y. L.;Zhang,Z. Y.;Chai,Z. F.,Unambiguous effects of lanthanum?Toxicology Letters 2007, 170 (1),94-96.
Chen,Z.;Meng,H.;Xing,G. M.;Chen,C. Y.;Zhao,Y. L.,Toxicological and biological effects of nanomaterials. International Journal of Nanotechnology 2007, 4 (1/2),179-196.
Wang,B.;Feng,W. Y.;Wang,T. C.;Jia,G.;Wang,M.;Shi,J. W.;Zhang,F.;Zhao,Y. L.;Chai,Z. F.,Acute toxicity of nano- and micro-scale zinc powder in healthy adult mice. Toxicology Letters 2006, 161 (2),115-123.
Feng,L. X.;Xiao,H. Q.;He,X.;Li,Z. J.;Li,F. L.;Liu,N. Q.;Zhao,Y. L.;Huang,Y. Y.;Zhang,Z. Y.;Chai,Z. F.,Neurotoxicological consequence of long-term exposure to lanthanum. Toxicology Letters 2006, 165 (2),112-120.
Feng,L. X.;Xiao,H. Q.;He,X.;Li,Z. J.;Li,F. L.;Liu,N. Q.;Chai,Z. F.;Zhao,Y. L.;Zhang,Z. Y.,Long-term effects of lanthanum intake on the neurobehavioral development of the rat. Neurotoxicol. Teratol. 2006, 28 (1),119-124.
Chen,Z.;Meng,H.;Xing,G. M.;Chen,C. Y.;Zhao,Y. L.;Jia,G. A.;Wang,T. C.;Yuan,H.;Ye,C.;Zhao,F.;Chai,Z. F.;Zhu,C. F.;Fang,X. H.;Ma,B. C.;Wan,L. J.,Acute toxicological effects of copper nanoparticles in vivo. Toxicology Letters 2006, 163 (2),109-120.
Wang,B.;Feng,W. Y.;Zhao,Y. L.;Xing,G. M.;Chai,Z. F.;Wang,H. F.;Jia,G.,Status of study on biological and toxicological effects of nanoscale materials. Science in China Series B-Chemistry 2005, 48 (5),385-394.
Jia,G.;Wang,H. F.;Yan,L.;Wang,X.;Pei,R. J.;Yan,T.;Zhao,Y. L.;Guo,X. B.,Cytotoxicity of carbon nanomaterials: Single-wall nanotube,multi-wall nanotube,and fullerene. Environmental Science & Technology 2005, 39 (5),1378-1383.
Chen,C. Y.;Xing,G. M.;Wang,J. X.;Zhao,Y. L.;Li,B.;Tang,J.;Jia,G.;Wang,T. C.;Sun,J.;Xing,L.;Yuan,H.;Gao,Y. X.;Meng,H.;Chen,Z.;Zhao,F.;Chai,Z. F.;Fang,X. H.,Multi hydroxylated [Gd@C82(OH)22]n nanoparticles: Antineoplastic activity of high efficiency and low toxicity. Nano Letters 2005, 5 (10),2050-2057.