姓 名:陈俊
职 称:研究员
Tel/Fax:010-88233212
Email: chenjun@ihep.ac.cn
通讯地址:中国科学院高能物理研究所
北京市石景山区玉泉路19号(乙院),100049
个人简历 :
中国科学院高能物理研究所研究员,硕士生导师、博士生副导师。2001年于武汉大学获化学学士学位。2007年,在武汉大学卓仁禧院士、黄世文教授指导下,获得博士学位。2007至2012年间先后赴美国韦恩州立大学David Oupicky教授课题组、加拿大曼尼托巴大学Mengqiu Xing教授课题组从事博士后、助理研究员工作。2013年以“高能物理研究所优秀人才引进”加入中科院高能所。2015年入选中国科学院青年创新促进会。主要从事生物医用高分子材料和纳米药物的研发,建立了多种智能性纳米药物、基因、细胞递送体系。目前已在国际重要学术期刊Adv Mater, Adv Funct Mater, Nano Letters, Small, Biomaterials, ACS Appl Mater Inter等发表论文40余篇,他人引用400余次。申请和授权专利五项。主持参与国家自然科学基金、科技部国家重大研究计划七项。国际重要学术期刊Adv Funct Mater, ACS Nano, Chem Mater, Small等的审稿人。
研究方向:
智能纳米药物递送体系、生物医用高分子材料。
代表性论文:
1. Tao Dong, Kaikai Wen, Jun Chen (co-1st), Jin Xie, Weili Fan, Han Ma, Lei Yang, Xiaoxi Wu, Fujian Xu, Aidong Peng, Hui Huang*, Significant Enhancement of Photothermal and Photoacoustic Efficiencies for Semiconducting Polymer Nanoparticles through Simply Molecular Engineering, Adv Funct Mater, 28, 1800135, 2018.
2. Hui Gao, Ying Bi, Xin Wang, Miao Wang, Mengxue Zhou, Huiru Lu, Jimin Gao, Jun Chen*, Yi Hu, Near-Infrared Guided Thermal-Responsive Nanomedicine against Orthotopic Superficial Bladder Cancer, ACS Biomater Sci Eng, 3 (12), 3628–3634, 2017.
3. Yi Liu, Heping Li*, Jin Xie, Mengxue Zhou, Hui Huang, Huiru Lu, Zhifang Chai, Jun Chen*, Yi Hu*, Facile construction of mitochondria-targeting nanoparticles for enhanced phototherapeutic effects, Biomater Sci, 5, 1022-1031, 2017.
4. Hui Gao, Ying Bi, Jun Chen*, Lirong Peng, Kaikai Wen, Pan Ji, Wefeng Ren, Xiaoqing Li, Ning Zhang, Jimin Gao*, Zhifang Chai, Yi Hu*, Near-Infrared Light-Triggered Switchable Nanoparticles for Targeted Chemo/Photothermal Cancer Therapy., ACS Appl Mater Interfaces, 8 (24), 15103–15112., 2016.
5. Yanping Qin; Jun Chen*; Ying Bi; Xiaohan Xu; Hui Zhou; Jimin Gao*; Yi Hu*, Yuliang Zhao; Zhifang Chai, Near-infrared light remote-controlled intracellular anti-cancer drug delivery using thermo/pH sensitive nanovehicle, Acta Biomater, 17, 201-209, 2015.
6. Jun Chen, Xiaozhong Qiu; Leyu Wang; Wen Zhong; Jiming Kong; Malcolm MQ Xing., Free-Standing Cell Sheet Assembled with Ultrathin Extracellular Matrix as an Innovative Approach for Biomimetic Tissues., Adv Funct Mater, 24, 2216-23, 2014,
7. Jun Chen, Min Shi; Pengmin Liu; Alex Ko; Wen Zhong; Wangjun Liao; Malcolm M.Q. Xing, Reducible polyamidoamine-magnetic iron oxide self-assembled nanoparticles for doxorubicin delivery., Biomaterials, 35, 1240-48, 2014,.
8. Jun Chen, Jun Ouyang, Jiming Kong, Wen Zhong, Malcolm Xing, Photo-cross-linked and pH-Sensitive Biodegradable Micelles for Doxorubicin Delivery. ACS Appl Mater Interfaces, 5, 3108–17, 2013.
9. Jun Chen, Shiwen Huang, Wenhai Lin, Renxi Zhuo, Tunable film degradation and sustained release of plasmid DNA from cleavable polycation/plasmid DNA multilayers under reductive conditions,Small,3,636-43, 2007.
10. Jun Chen, Ximing Xia, Shiwen Huang, Renxi Zhuo, A cleavable-polycation template method for the fabrication of noncrosslinked, porous polyelectrolyte multilayered films,Adv Mater, 19,979-83, 2007.